Handbook of Drug Screening, Second Edition (Drugs and the Pharmaceutical Sciences)
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Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery.
With extensively updated content and 21 new chapters, this text examines:
- quality and efficiency of drug target validation and potential drug compound selection
- reducing assay costs and improvement in assay technology
- data quality improvement
- trends in drug discovery
- how drug screening can minimize adverse drug effects
- recent advancements, including: high content screening; protein-protein interactions; high-throughput crystallization; lead optimization; chemoinformatics and microfluidics technologies; target validation by genomics, proteomics, and siRNA; structure-based drug design; automation; and medicinal chemistry
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